| 21/07/2021 Friendly |  Walsall | 0 - 4 |  Aston Villa |
| 24/07/2021 Friendly |  Stoke City | 2 - 0 | Aston Villa |
| 31/07/2021 Friendly |  Bristol City | 0 - 3 | Aston Villa |
| 08/08/2021 Friendly | Aston Villa | 3 - 1 |  Salernitana |
| 14/08/2021 Premier League |  Watford | 3 - 2 | Aston Villa |
| 21/08/2021 Premier League | Aston Villa | 2 - 0 |  Newcastle |
| 24/08/2021 EFL Cup |  Barrow AFC | 0 - 6 | Aston Villa |
| 28/08/2021 Premier League | Aston Villa | 1 - 1 |  Brentford |
| 11/09/2021 Premier League |  Chelsea | 3 - 0 | Aston Villa |
| 18/09/2021 Premier League | Aston Villa | 3 - 0 |  Everton |
| 22/09/2021 EFL Cup | Chelsea | 1 - 1 Chelsea win 4-3 on Pens. | Aston Villa |
| 25/09/2021 Premier League |  Man. Utd | 0 - 1 | Aston Villa |
| 03/10/2021 Premier League |  Tottenham | 2 - 1 | Aston Villa |
| 16/10/2021 Premier League | Aston Villa | 2 - 3 |  Wolves |
| 22/10/2021 Premier League |  Arsenal | 3 - 1 | Aston Villa |
| 31/10/2021 Premier League | Aston Villa | 1 - 4 |  West Ham |
| 05/11/2021 Premier League |  Southampton | 1 - 0 | Aston Villa |
| 20/11/2021 Premier League | Aston Villa | 2 - 0 |  Brighton |
| 27/11/2021 Premier League |  Crystal Palace | 1 - 2 | Aston Villa |
| 01/12/2021 Premier League | Aston Villa | 1 - 2 |  Man. City |
| 05/12/2021 Premier League | Aston Villa | 2 - 1 |  Leicester City |
| 11/12/2021 Premier League |  Liverpool | 1 - 0 | Aston Villa |
| 14/12/2021 Premier League |  Norwich | 0 - 2 | Aston Villa |
| 26/12/2021 Premier League | Aston Villa | 1 - 3 | Chelsea |
| 02/01/2022 Premier League | Brentford | 2 - 1 | Aston Villa |
| 10/01/2022 FA Cup | Man. Utd | 1 - 0 | Aston Villa |
| 15/01/2022 Premier League | Aston Villa | 2 - 2 | Man. Utd |
| 22/01/2022 Premier League | Everton | 0 - 1 | Aston Villa |
| 09/02/2022 Premier League | Aston Villa | 3 - 3 |  Leeds |
| 13/02/2021 Premier League | Newcastle | 1 - 0 | Aston Villa |
| 19/02/2021 Premier League | Aston Villa | 0 - 1 | Watford |
| 26/02/2021 Premier League | Brighton | 0 - 2 | Aston Villa |
| 05/03/2021 Premier League | Aston Villa | 4 - 0 | Southampton |
| 10/03/2022 Premier League | Leeds | 0 - 3 | Aston Villa |
| 13/03/2021 Premier League | West Ham | 2 - 1 | Aston Villa |
| 19/03/2021 Premier League | Aston Villa | 0 - 1 | Arsenal |
| 02/04/2021 Premier League | Wolves | 2 - 1 | Aston Villa |
| 09/04/2021 Premier League | Aston Villa | 0 - 4 | Tottenham |
| 23/04/2021 Premier League | Leicester City | 0 - 0 | Aston Villa |
| 30/04/2021 Premier League | Aston Villa | 2 - 0 | Norwich |
| 07/05/2021 Premier League |  Burnley | 1 - 3 | Aston Villa |
| 10/05/2021 Premier League | Aston Villa | 1 - 2 | Liverpool |
| 15/05/2021 Premier League | Aston Villa | 1 - 1 | Crystal Palace |
| 19/05/2022 Premier League | Aston Villa | 1 - 1 | Burnley |
| 22/05/2021 Premier League | Man. City | 3 - 2 | Aston Villa |